With Ranitidine off the shelves, finding the right alternative for heartburn and acid indigestion relief is crucial. In 2025, options like Zantac 360, which contains famotidine, offer an effective Over-The-Counter solution. This article explores various Ranitidine substitutes, highlighting their benefits and drawbacks to help you make an informed decision. Whether you need immediate heartburn relief or a prescription-strength medicine, this guide will provide clarity.